[IEEE CAS04/ED15/EP21/PHO36 Seminar] Current Research Status and Application Prospects of Neuron-on-a-chip
July 30 @ 10:00 am - 12:00 pm
IEEE CAS Toronto is proud to invite you to a seminar by Dr. Chen Jie of Fudan <a href="http://University.
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Join us Wednesday, 30 July 2025 at 10AM (ET) on University of Toronto main campus. Refreshments will be <a href="http://served.
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With the advancement of microfluidic and organoid technologies, neuron-on-a-chip platforms have demonstrated tremendous potential in precisely replicating the three-dimensional structure of the brain, simulating intercellular interactions, and reconstructing in vitro physiological models. On one hand, compared to traditional two-dimensional cell cultures, neuron-on-a-chip systems can not only construct more complex physiological architectures but also provide a dynamically controllable developmental environment for neural tissues. On the other hand, compared to animal models, brain-on-a-chip techno
logy not only effectively addresses the limitations in the number of available animal models, but also alleviates, to some extent, the ethical concerns associated with animal experiments. Through induced pluripotent stem cell (iPSC) technology, we can directly model human brain pathological phenotypes on chips, overcoming challenges posed by interspecies differences in animal models, and enabling the investigation of key events in the progression of human neurological disorders. In addition, neuron-on-a-chip systems can be integrated with other organoid tissues on microfluidic chips to create multi-organ-on-a-chip platforms. Compared to single-organ chips, multi-organ systems can reconstruct multiple human tissue organoids in vitro, enabling precise simulation of inter-organ <a href="http://interactions.
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Speaker(s): Dr. Chen Jie,
Room: BA024, Bldg: Bahen Centre for Information Technology, Toronto, Ontario, Canada